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Biological Evaluation of Medical Devices
Key guidance on how to use the ISO 10993 series of standards and successfully apply a risk management approach to the biological evaluation of medical devices.
Includes: Interactive workshops and discussion sessions
Course overview
The ISO 10993 series of standards covering biological evaluation of medical devices is well established and regulatory authorities worldwide expect compliance. In Europe, compliance with the standards is the easiest way to meet the essential product safety requirements of the MDR and understanding a risk management approach to biological safety is essential.
This seminar will provide key guidance on how to use the standards and successfully apply a risk management approach to the biological evaluation of medical devices. There will be plenty of time during the programme for interactive discussion with experts in this field.
Benefits of attending:
- Understand biological risk management
- Clarify the requirements of ISO 10993-1
- Learn what endpoints need to be addressed in a biological risk assessment
- Establish how much chemical characterisation is necessary
- Hear the FDA’s approach to ISO 10993
- Better understand Medical Device Directive (MDD) safety requirements vs the Medical Device Regulation (MDR) safety requirements
- Know how extractables and leachables impact on medical device safety
- Discuss the Japanese and Chineserequirements
Who should attend?
The event will be of particular importance to those in the medical device industry from the following departments:
- Regulatory affairs
- R&D
- Product safety/toxicology
- Analytical chemistry
- Risk assessment and risk management
- Materials research and evaluation
It will also be of interest to regulatory authorities, Notified Bodies and CROs supporting the medical device industry.
Programme day one
An introduction to medical devices
An introduction to biocompatibility
Biocompatibility vs biological safety
ISO 10993 history and development
ISO 10993 structure and content
ISO/TR 15499 and 10993/1 (2018)
Relationship between 10993 and 14971
Medical device categorisation for biological risk assessment
The move away from in vivo testing
Endpoints to be addressed in a biological risk assessment
Chemical characterisation vs chemical information
Physical characterisation
Guidance on technical aspects of specific biocompatibility tests
Programme day two
Extractables and leachables testing – when and why?
Risk assessment using E&L data
MDD safety requirements
MDR safety requirements
Good Laboratory Practice (GLP)
The 510(K) process
FDA’s take on ISO 10993
Japanese requirements
Chinese requirements
MDR – gap analysis of existing data
Change management – impact on biological risk assessment
Questions and final discussion
Interactive workshops and discussion sessions will take place throughout the two days
Presenters
Philip Clay
Philip Clay is Director and principal toxicologist with Chorley Consulting. He is a UK and European registered toxicologist and specialises in product safety assessment with over 30 years’ experience in toxicology and safety assessment. He is a BSI committee member on CH/194 (Biological evaluation of medical devices) and Principal Expert for WG6 (Mutagenicity, carcinogenicity and reproductive toxicity).
Philip established his reputation as a genetic toxicologist working within the agrochemical, chemical and pharmaceutical industries. He has contributed to many expert panels, helping to shape the testing guidelines and strategies in place today. More recently, this experience and depth of understanding has been applied to designing safety assessment programmes for medical devices and consumer healthcare products for a wide range of clients. Philip is presently a member of a Consumer Healthcare Products Association (CHPA) expert group lobbying US FDA regarding the use of in vitro data in the assessment of the biocompatibility of medical devices.
He has extensive experience in the biological safety evaluation of a wide range of medical devices from Class 1 consumer healthcare devices through to Class 3 implantable devices. He is an experienced speaker at scientific conferences and has delivered training on biological safety evaluation around the world.
Janine Ingleby
Janine Ingleby is a Senior Safety Assessor with Chorley Consulting. She holds a MSc in Global aquatic biodiversity and a BSc in Molecular biology and biotechnology, both from the University of Hull. She has over 10 years of regulatory and product safety experience within FMCG and the Fragrance industry. She also holds a Prince2 practitioner qualification in project management. Janine has a great depth of knowledge in the regulation of cosmetics and fragrances as well as having toxicological data analysis skills for use in risk assessments of medicines, medical devices, cosmetics and general products.
She is an experienced presenter with particular strengths in the regulatory and quality management aspects of the biological evaluation of medical devices.
Book now
| 25-26 Nov 2020 | |||
| 25-26 Nov 2020 | Rembrandt Hotel, London | GBP 1,499.00 EUR 2,099.00 USD 2,338.00 + VAT @ 20.00% |
Online registration unavailable: this date is nearing full capacity; please call us on 020 7749 4730 to register. |
| 18-19 May 2021 | |||
| 18-19 May 2021 | Venue not yet confirmed | + VAT @ 20.00% |
Enrol now |
| 23-24 Nov 2021 | |||
| 23-24 Nov 2021 | Venue not yet confirmed | + VAT @ 20.00% |
Enrol now |
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Previous customers include...
- ABBOTT IRELAND
- Allergan Medical
- BAUSCH & LOMB INC
- Bespak
- Biocompatibles UK Ltd
- BioTop Medical
- Cardinal Health
- Covidien
- Denish Medical Devices Cert.
- Depuy CMW
- Elcam Medical ACAL
- Fresenius HemoCare Netherlands BV
- ITL LIMITED
- LAB Research (Scantox)
- Mentor Medical Systems B.V.
- Novo Nordisk A/S
- Omron Healthcare Europe BV
- Pall Europe Limited
- QUINTILES CONSULTING - MTC
- RCC LTD
- Renishaw plc
- Russell Square Quality Associates Limited
- Smith & Nephew Wound Management
- Smiths Medical International Limited
- Smiths Medical International Ltd
- Summit Medical Ltd
- Synthes GmbH
- Systagenix Wound Management
- Tissue Science Laboratories PLC
- William Cook Europe ApS
“It was a good course with good shared discussion about many topics and issues. The course material was well organized. ”
Elen Lasri, Regulatory Affairs Specialist, Elcam Medical ACAL, Oct 19
“I learned a lot from this course, the speakers were great and they encouraged questions from the attendees. The quiz summarized each part well. My overall opinion is very positive and I would recommend it to my colleagues.”
Avital Levertov, Regulatory Affairs Manager, Elcam Medical ACAL, Oct 19