Basic Principles of Pharmacokinetics

An introduction and overview of the main principles and concepts of Pharmacokinetics relating to drug discovery and development.

Course Overview

A basic introduction and overview of the main principles and concepts of pharmacokinetics relating to drug discovery and development, including consideration of:

  • Intravenous infusion and multiple dosing
  • Distribution dynamics, concentration – and time-dependent kinetics
  • Linking pharmacokinetics to pharmacodynamics
  • In vitro – in vivo extrapolation

Why you should attend

This two-day course is intended to provide a basic knowledge and understanding of the main principles and concepts of pharmacokinetics and their application in drug discovery and development. The lectures will be interspersed with workshop problem solving sessions. There will be equations, but they will be small ones!

Who should attend

This workshop will be of interest and benefit to all those requiring a basic knowledge of pharmacokinetics and pharmacodynamics.

Programme - Day one

Introduction and welcome

Intravenous bolus

  • Volume of distribution
  • Clearance
  • Elimination of half-life

Refreshments

Workshop one: Problem set 1

Determinants of distribution and clearance

Lunch

Workshop two: Problem set 2

Refreshments

Oral drug administration
  • Bioavailability
  • Bioequivalence

Workshop three: Problem set 3

End of day one

Programme - Day two

Prolonging duration

Workshop four: Problem set 4

Refreshments

Advanced level pharmacokinetics

  • Distribution dynamics
  • Concern and time dependence
  • Metabolite kinetics

Workshop five: Problem set 5

Lunch

Pharmacodynamics

Workshop six: Problem set 6

Refreshments

In Vitro – In Vivo Extrapolation

Close of meeting

Bespoke training

We can customise this course to meet the requirements of your organisation. Contact us to discuss your training requirements.

Previous customers include...

  • Abbot Laboratories Limited
  • BI Pharma GmbH & Co KG
  • Chanelle Medical
  • Gilead Sciences International Ltd
  • MHRA